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EGFR/ErbB-2/ErbB-4 inhibitor-2

This small molecule is a potent, cell-permeable dual inhibitor of EGFR and ErbB2 (HER2), with IC50 values of 20 nM and 79 nM, respectively. It is widely used in cancer research to study receptor tyrosine kinase signaling in both cellular assays and in vivo tumor models.

Product Specifications

CAS Number

179248-61-4

Product Name Alternative

C-ErbB2, ErbB4, EGFR, EGFR/ErbB 2/ErbB 4 inhibitor 2, EGFR/ErbB2 Inhibitor, EGFR/ErbB2/ErbB4 inhibitor2, EGFR/ErbB-2/ErbB-4 inhibitor-2, Epidermal growth factor receptor, ErbB2, ErbB-1, HER1, HN5, Inhibitor, inhibit

Field of Research

Cardiovascular Research, Pharmacology & Drug Discovery; Cell Biology, Signal Transduction

Purity

98.10% (May vary between batches)

Solubility

DMSO:55 mg/mL (141.96 mM) ;10% DMSO+90% Corn Oil:2.5 mg/mL (6.45 mM)

Smiles

COc1cc2ncnc (Nc3ccc (OCc4ccccc4) cc3) c2cc1OC

Molecular Formula

C23H21N3O3

Molecular Weight

387.43

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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