EGFR/ErbB-2/ErbB-4 inhibitor-2
This small molecule is a potent, cell-permeable dual inhibitor of EGFR and ErbB2 (HER2), with IC50 values of 20 nM and 79 nM, respectively. It is widely used in cancer research to study receptor tyrosine kinase signaling in both cellular assays and in vivo tumor models.
Product Specifications
CAS Number
179248-61-4
Product Name Alternative
C-ErbB2, ErbB4, EGFR, EGFR/ErbB 2/ErbB 4 inhibitor 2, EGFR/ErbB2 Inhibitor, EGFR/ErbB2/ErbB4 inhibitor2, EGFR/ErbB-2/ErbB-4 inhibitor-2, Epidermal growth factor receptor, ErbB2, ErbB-1, HER1, HN5, Inhibitor, inhibit
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery; Cell Biology, Signal Transduction
Purity
98.10% (May vary between batches)
Solubility
DMSO:55 mg/mL (141.96 mM) ;10% DMSO+90% Corn Oil:2.5 mg/mL (6.45 mM)
Smiles
COc1cc2ncnc (Nc3ccc (OCc4ccccc4) cc3) c2cc1OC
Molecular Formula
C23H21N3O3
Molecular Weight
387.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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