MeBIO
MeBIO is a small molecule aryl hydrocarbon receptor agonist that also inhibits GSK-3 and CDK1/CyclinB with IC50 values of 44 and 55 μM, respectively, while showing no effect on GSK-3β. It serves as a useful research tool for studying AhR signaling and cell cycle regulation in various in vitro biochemical and cellular assays.
Product Specifications
CAS Number
667463-95-8
Product Name Alternative
Glycogen synthase kinase-3, Glycogen synthase kinase 3, GSK3, GSK-3, MeBIO, Inhibitor, inhibit, aryl hydrocarbon receptor, Aryl Hydrocarbon Receptor, Aryl Hydrocarbon Receptor (AhR), ArylHydrocarbonReceptor, Agonist, AhR, Cyclin dependent kinase, CDK5/p25, CDK, CDK1/CyclinB
Field of Research
Cell Biology, Immunology & Inflammation, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.84% (May vary between batches)
Solubility
DMSO:9 mg/mL (24.31 mM)
Smiles
CN1C (=O) \C (=C2/Nc3ccccc3/C/2=N\O) c2ccc (Br) cc12
Molecular Formula
C17H12BrN3O2
Molecular Weight
370.2
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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