PD 198306
PD 198306 is a selective MEK inhibitor exhibiting antihyperalgesic properties. It effectively attenuates the Streptozocin-induced elevation of active ERK1 levels, making it a useful research tool for studying MAPK/ERK signaling in diabetic neuropathy models both in vitro and in vivo.
Product Specifications
CAS Number
212631-61-3
Product Name Alternative
Rabies, phosphatases, phosphate, screening, RNA, antihyperalgesic, drug, inhibit, Inhibitor, kinases, neuropathic, Mitogen-activated protein kinase kinase, mitogen-activated protein, PD 198306, PD198306, PD-198306, pain, ERK, inositol, interference, MAPK, MAP2K, MAPKK, MEK
Field of Research
Signal Transduction
Purity
99.66% (May vary between batches)
Solubility
DMSO:45 mg/mL (94.49 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (10.5 mM)
Smiles
N (C1=C (C (NOCC2CC2) =O) C=C (F) C (F) =C1F) C3=C (C) C=C (I) C=C3
Molecular Formula
C18H16F3IN2O2
Molecular Weight
476.23
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
029262 100 µg
PRDX1 (Peroxiredoxin-1, Natural Killer Cell-enhancing Factor A, NKEF-A, Proliferation-associated Gene Protein, PAG, Thioredoxin Peroxidase 2, Thioredoxin-dependent Peroxide Reductase 2, PAGA, PAGB, TDPX2) (FITC)
Sign In for Pricing
View Details 
K0455103 1.0 µg DNA
CIZ1 sgRNA CRISPR Lentivector (Human) (Target 2)
Sign In for Pricing
View Details ZA451012-02 100 µg
Recombinant Zebrafish IL4 Protein, N-GST & C-His
Sign In for Pricing
View Details