PD 198306
PD 198306 is a selective MEK inhibitor exhibiting antihyperalgesic properties. It effectively attenuates the Streptozocin-induced elevation of active ERK1 levels, making it a useful research tool for studying MAPK/ERK signaling in diabetic neuropathy models both in vitro and in vivo.
Product Specifications
CAS Number
212631-61-3
Product Name Alternative
Rabies, phosphatases, phosphate, screening, RNA, antihyperalgesic, drug, inhibit, Inhibitor, kinases, neuropathic, Mitogen-activated protein kinase kinase, mitogen-activated protein, PD 198306, PD198306, PD-198306, pain, ERK, inositol, interference, MAPK, MAP2K, MAPKK, MEK
Field of Research
Signal Transduction
Purity
99.66% (May vary between batches)
Solubility
DMSO:45 mg/mL (94.49 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (10.5 mM)
Smiles
N (C1=C (C (NOCC2CC2) =O) C=C (F) C (F) =C1F) C3=C (C) C=C (I) C=C3
Molecular Formula
C18H16F3IN2O2
Molecular Weight
476.23
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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