Vacuolin-1
Vacuolin-1 is a cell-permeable small molecule that potently and selectively inhibits PIKfyve. It blocks Ca2+-dependent lysosomal exocytosis and impairs lysosomal maturation, thereby inhibiting late-stage autophagy. This compound is widely used in vitro and in vivo to study lysosomal function, membrane trafficking, and autophagic flux.
Product Specifications
CAS Number
351986-85-1
Product Name Alternative
PIKfyve, Vacuolin 1, Vacuolin1, Vacuolin-1, Autophagy, membrane repair, HeLa cells, exocytosis, Fab1, Inhibitor, inhibit
Field of Research
Cell Biology
Purity
>98%
Form
Powder
Solubility
Soluble in DMSO (35 mg/ml)
Smiles
Ic1cccc (\C=N\Nc2nc (nc (n2) N2CCOCC2) N (c2ccccc2) c2ccccc2) c1
Molecular Formula
C26H24IN7O
Molecular Weight
577.4
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
3-Iodobenzaldehyde,2-[4- (diphenylamino) -6- (4-morpholinyl) -1,3,5-triazin-2-yl]hydrazone
Available Sizes
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