XAP044
XAP044 is a selective mGlu7 receptor antagonist. It blocks lateral amygdala long-term potentiation (LTP) in wild-type mouse brain slices with an IC50 of 88 nM. This compound is a valuable research tool for investigating synaptic plasticity, fear memory, and anxiety-related disorders in both in vitro and in vivo models.
Product Specifications
CAS Number
196928-50-4
Product Name Alternative
CNS, brain exposure, antidepressant, anxiolytic-like, anti-stress, mGluR, mGlu7, Metabotropic glutamate receptors, neurotransmission, inhibit, Inhibitor, wide spectrum, XAP 044, XAP044, XAP-044
Field of Research
Neuroscience
Purity
97.41% (May vary between batches)
Solubility
DMSO:60 mg/mL (157.84 mM)
Smiles
OC1=CC2=C (C=C1) C (=O) C (OC1=CC=C (I) C=C1) =CO2
Molecular Formula
C15H9IO4
Molecular Weight
380.13
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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