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7BIO

7-Bromoindirubin-3'-oxime (7BIO) is a cell death inducer that operates independently of caspases and apoptosis. It functions as a multi-kinase inhibitor, targeting FLT3, DYRK1A, DYRK2, Aurora B, and Aurora C. This compound is utilized in vitro to study non-apoptotic cell death mechanisms in cancer research.

Product Specifications

CAS Number

916440-85-2

Product Name Alternative

Tau hyper-phosphorylation, synaptic impairments, Glycogen synthase kinase-3, Glycogen synthase kinase 3, FLT3, GSK-3, GSK3β, Inhibitor, neuroinflammation, inhibit, activation of astrocytes and microglia, 7BIO, AuroraKinase, Aurora Kinase, Aurora B, Aurora C, Aβ oligomer, DYRK1A, DYRK2, Cyclin dependent kinase, cognitive impairment, CDK5, CDK

Field of Research

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Purity

99.67% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.62 mM) ; Ethanol:Soluble; DMSO:36.67 mg/mL (102.96 mM)

Smiles

O\N=C1\C (\Nc2ccccc\12) =C1\C (=O) Nc2c1cccc2Br

Molecular Formula

C16H10BrN3O2

Molecular Weight

356.17

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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