7BIO
7-Bromoindirubin-3'-oxime (7BIO) is a cell death inducer that operates independently of caspases and apoptosis. It functions as a multi-kinase inhibitor, targeting FLT3, DYRK1A, DYRK2, Aurora B, and Aurora C. This compound is utilized in vitro to study non-apoptotic cell death mechanisms in cancer research.
Product Specifications
CAS Number
916440-85-2
Product Name Alternative
Tau hyper-phosphorylation, synaptic impairments, Glycogen synthase kinase-3, Glycogen synthase kinase 3, FLT3, GSK-3, GSK3β, Inhibitor, neuroinflammation, inhibit, activation of astrocytes and microglia, 7BIO, AuroraKinase, Aurora Kinase, Aurora B, Aurora C, Aβ oligomer, DYRK1A, DYRK2, Cyclin dependent kinase, cognitive impairment, CDK5, CDK
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.67% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.62 mM) ; Ethanol:Soluble; DMSO:36.67 mg/mL (102.96 mM)
Smiles
O\N=C1\C (\Nc2ccccc\12) =C1\C (=O) Nc2c1cccc2Br
Molecular Formula
C16H10BrN3O2
Molecular Weight
356.17
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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