CCG-100602
CCG-100602 is a cell-permeable inhibitor of RhoA/C-mediated SRF transcriptional activity, with an IC50 of 9.8 μM in PC-3 prostate cancer cells. This compound is a useful research tool for studying Rho GTPase signaling pathways in cancer cell biology and metastasis, both in vitro and in vivo.
Product Specifications
CAS Number
1207113-88-9
Product Name Alternative
CCG100602, CCG-100602, CCG 100602, nuclear, localization, Inhibitor, myocardin, inhibit, MRTF-A, SRF, rho, serum, Ras, transcription
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Purity
99.58% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:1 mg/mL (2.09 mM) ; DMSO:100 mg/mL (208.85 mM)
Smiles
FC (F) (F) c1cc (cc (c1) C (F) (F) F) C (=O) N1CCCC (C1) C (=O) Nc1ccc (Cl) cc1
Molecular Formula
C21H17ClF6N2O2
Molecular Weight
478.82
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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