HA 155
HA 155 (Autotaxin Inhibitor IV) is a potent and selective boronic acid inhibitor of autotaxin (ATX), exhibiting an IC50 of 5.7 nM through covalent interaction with the catalytic threonine. This tool compound is utilized in vitro and in vivo to investigate the lysophosphatidic acid (LPA) signaling pathway in cancer, fibrosis, and inflammation research.
Product Specifications
CAS Number
1229652-22-5
Product Name Alternative
Pain, inhibit, Inflammation, Inhibitor, Fibrotic diseases, HA155, HA-155, HA 155, (E/Z) -HA155, Cancer, ATX (autotaxin), Autotaxin, Autotaxin Inhibitor IV, Angiogenesis, Phosphodiesterase (PDE)
Field of Research
Metabolism Research
Purity
98.92% (May vary between batches)
Solubility
DMSO:Slightly soluble
Smiles
C (=C1C (=O) N (CC2=CC=C (F) C=C2) C (=O) S1) C3=CC=C (OCC4=CC=C (B (O) O) C=C4) C=C3
Molecular Formula
C24H19BFNO5S
Molecular Weight
463.29
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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