3PO
3PO is a small-molecule PFKFB3 inhibitor (IC50: 22.9 μM) that impedes cancer cell proliferation by disrupting glycolysis. It reduces glucose uptake and lowers levels of Fru-2,6-BP, lactate, and ATP, making it a useful tool for studying cancer metabolism in both in vitro and in vivo models.
Product Specifications
CAS Number
18550-98-6
Product Name Alternative
Small-molecule, PFKFB3, chemotherapeutic agents, Autophagy, 3PO, adenocarcinoma cell, inhibit, isozyme, Inhibitor, human malignant hematopoietic
Field of Research
Cardiovascular Research, Cell Biology
Purity
>98%
Bioactivity
6-Phosphofructo-2-kinase (PFKFB3) inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 15 mg/ml) or in Ethanol (up to 5 mg/ml)
Smiles
O=C (\C=C\c1cccnc1) c1ccncc1
Molecular Formula
C13H10N2O
Molecular Weight
210.23
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
(2E) -3- (3-Pyridinyl) -1- (4-pyridinyl) -2-propen-1-one
Available Sizes
Frequently Asked Questions
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