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Alflutinib

Alflutinib (Firmonertinib) is a small molecule EGFR inhibitor targeting both activating mutations and the T790M resistance mutation. It is used in research applications, including in vitro and in vivo studies, to investigate its antitumor efficacy in models of non-small cell lung cancer (NSCLC) .

Product Specifications

CAS Number

1869057-83-9

Product Name Alternative

CYP3A4, Alflutinib, cancer, ASK 120067, ASK120067, ASK-120067, AST 2818, AST2818, AST-2818, esistant mutation, Furmonertinib, ErbB-1, Epidermal growth factor receptor, EGFR, Firmonertinib, Inhibitor, HER1, inhibit, NSCLC, T790M

Field of Research

Cardiovascular Research, Metabolism Research, Signal Transduction

Purity

99.61% (May vary between batches)

Solubility

DMSO:10.83 mg/mL (19.05 mM)

Smiles

CN1C=C (C=2C1=CC=CC2) C3=NC (NC4=C (OCC (F) (F) F) N=C (N (CCN (C) C) C) C (NC (C=C) =O) =C4) =NC=C3

Molecular Formula

C28H31F3N8O2

Molecular Weight

568.59

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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