Bavdegalutamide
Bavdegalutamide (ARV-110) is an orally bioavailable PROTAC degrader targeting the androgen receptor (AR) . It effectively degrades clinically relevant AR mutants, even in high androgen conditions, and is suitable for in vitro and in vivo prostate cancer research, demonstrating a favorable preclinical safety profile.
Product Specifications
CAS Number
2222112-77-6
Product Name Alternative
ARV 110, ARV110, ARV-110, Bavdegalutamide, androgen, AndrogenReceptor, Androgen Receptor, cancer, castration-resistant prostate cancer, Inhibitor, inhibit, metastatic, prostate, receptor
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
97.17% (May vary between batches)
Solubility
DMSO:41.67 mg/mL (51.3 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:1 mg/mL (1.23 mM)
Smiles
O=C1C=2C (C (=O) N1C3C (=O) NC (=O) CC3) =CC (F) =C (C2) N4CCN (CC5CCN (CC5) C6=CC=C (C (N[C@@H]7CC[C@@H] (OC8=CC (Cl) =C (C#N) C=C8) CC7) =O) N=N6) CC4
Molecular Formula
C41H43ClFN9O6
Molecular Weight
812.29
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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