JNJ-7777120
JNJ-7777120 is a potent and selective non-imidazole histamine H4 receptor antagonist with a Ki of 4.5 nM and >1000-fold selectivity over other histamine receptors. It is widely used in research to investigate the role of H4R in inflammation, allergy, and pruritus in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
459168-41-3
Product Name Alternative
JNJ 7777120, inhibit, JNJ7777120, JNJ-7777120, HistamineReceptor, Histamine Receptor, Inhibitor, H4 receptor
Field of Research
Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery
Purity
99.71% (May vary between batches)
Solubility
DMSO:40 mg/mL (144.01 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.2 mM)
Smiles
C (=O) (C1=CC=2C (N1) =CC=C (Cl) C2) N3CCN (C) CC3
Molecular Formula
C14H16ClN3O
Molecular Weight
277.75
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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