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JNJ-7777120

JNJ-7777120 is a potent and selective non-imidazole histamine H4 receptor antagonist with a Ki of 4.5 nM and >1000-fold selectivity over other histamine receptors. It is widely used in research to investigate the role of H4R in inflammation, allergy, and pruritus in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

459168-41-3

Product Name Alternative

JNJ 7777120, inhibit, JNJ7777120, JNJ-7777120, HistamineReceptor, Histamine Receptor, Inhibitor, H4 receptor

Field of Research

Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery

Purity

99.71% (May vary between batches)

Solubility

DMSO:40 mg/mL (144.01 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.2 mM)

Smiles

C (=O) (C1=CC=2C (N1) =CC=C (Cl) C2) N3CCN (C) CC3

Molecular Formula

C14H16ClN3O

Molecular Weight

277.75

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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