GW 4064
GW 4064 is a potent and selective synthetic agonist of the farnesoid X receptor (FXR), exhibiting an EC50 of 65 nM. This tool compound is widely used in both in vitro and in vivo research to investigate FXR's role in bile acid homeostasis, metabolic disorders, and liver diseases.
Product Specifications
CAS Number
278779-30-9
Product Name Alternative
Inhibitor, NR1H4, inhibit, GW 4064, GW4064, GW-4064, FXR, Autophagy
Field of Research
Cell Biology, Metabolism Research
Purity
97.47% (May vary between batches)
Solubility
DMSO:50 mg/mL (92.11 mM) ; Ethanol:5.4 mg/mL (9.95 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.68 mM)
Smiles
CC (C) c1onc (c1COc1ccc (C=Cc2cccc (c2) C (O) =O) c (Cl) c1) -c1c (Cl) cccc1Cl
Molecular Formula
C28H22Cl3NO4
Molecular Weight
542.84
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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