GSK-114
GSK-114 is a potent and highly selective TNNI3K inhibitor (IC50 = 25 nM), demonstrating excellent kinase selectivity and oral bioavailability. Its favorable pharmacokinetic profile enables its application in cellular assays and in vivo models for cardiovascular and cardiac hypertrophy research.
Product Specifications
CAS Number
1301761-96-5
Product Name Alternative
Cardiac diseases, GSK 114, GSK114, GSK-114, heart tissue, inhibit, Inhibitor, oral, selective, TNNI3 Interacting Kinase (TNNI3K), TNNI3K
Field of Research
Signal Transduction
Purity
98.03% (May vary between batches)
Solubility
DMSO:5.5 mg/mL (13.17 mM)
Smiles
CNS (=O) (=O) c1ccc (N (C) C) c (Nc2ncnc3cc (OC) c (OC) cc23) c1
Molecular Formula
C19H23N5O4S
Molecular Weight
417.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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