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JNJ-38158471

JNJ-38158471 (CS-2660) is a potent and selective oral VEGFR2 inhibitor (IC50=40 nM) with additional activity against Ret and Kit kinases. This compound is suitable for in vitro biochemical assays and in vivo research models investigating angiogenesis and oncogenic kinase signaling pathways.

Product Specifications

CAS Number

951151-97-6

Product Name Alternative

Malignancies, Inhibitor, inhibit, Kit, JNJ38158471, JNJ-38158471, JNJ 38158471, cancer, CD117, c-Kit, cKit, CS2660, CS-2660, CS 2660, cRET, VEGFR, VEGFR-2, VEGFR2, Vascular endothelial growth factor receptor, SCFR, RET, Ret

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Purity

97.08% (May vary between batches)

Solubility

10% DMSO+90% Corn Oil:2 mg/mL (5.48 mM) ; DMSO:30 mg/mL (82.24 mM)

Smiles

CCNC (=O) Nc1ccc (Oc2ncnc (N) c2\C=N\OC) cc1Cl

Molecular Formula

C15H17ClN6O3

Molecular Weight

364.79

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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