JNJ-38158471
JNJ-38158471 (CS-2660) is a potent and selective oral VEGFR2 inhibitor (IC50=40 nM) with additional activity against Ret and Kit kinases. This compound is suitable for in vitro biochemical assays and in vivo research models investigating angiogenesis and oncogenic kinase signaling pathways.
Product Specifications
CAS Number
951151-97-6
Product Name Alternative
Malignancies, Inhibitor, inhibit, Kit, JNJ38158471, JNJ-38158471, JNJ 38158471, cancer, CD117, c-Kit, cKit, CS2660, CS-2660, CS 2660, cRET, VEGFR, VEGFR-2, VEGFR2, Vascular endothelial growth factor receptor, SCFR, RET, Ret
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Purity
97.08% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:2 mg/mL (5.48 mM) ; DMSO:30 mg/mL (82.24 mM)
Smiles
CCNC (=O) Nc1ccc (Oc2ncnc (N) c2\C=N\OC) cc1Cl
Molecular Formula
C15H17ClN6O3
Molecular Weight
364.79
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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