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MDR-652

MDR-652 is a potent, nonpungent TRPV1 agonist with high affinity (Ki: 11.4 nM hTRPV1) and functional potency (EC50: 5.05 nM hTRPV1) . Its strong topical analgesic properties support research in pain pathways, inflammation, and neurobiology, applicable in both in vitro receptor studies and in vivo models of nociception.

Product Specifications

CAS Number

1933528-96-1

Product Name Alternative

Activity, analgesic, MDR 652, MDR652, MDR-652, hTRPV1, ligand, Inhibitor, inhibit, pain, neuropathic, Transient receptor potential channels, TRP Channel, TRPChannel, TRPV Channel, TRPV1, TRPVChannel

Field of Research

Pharmacology & Drug Discovery

Purity

95.04% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (11.16 mM) ; DMSO:249 mg/mL (555.87 mM)

Smiles

CC (C) (C) c1nc (c (CNC (=O) Nc2ccc (CO) c (F) c2) s1) -c1cccc (Cl) c1

Molecular Formula

C22H23ClFN3O2S

Molecular Weight

447.95

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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