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Paritaprevir

Paritaprevir (ABT450) is a potent small molecule inhibitor targeting the HCV NS3/4A serine protease. It demonstrates high antiviral activity with EC50 values of 1 nM against HCV genotype 1a and 0.21 nM against genotype 1b. This compound is a key research tool for studying HCV replication and antiviral mechanisms in biochemical and cellular assays.

Product Specifications

CAS Number

1216941-48-8

Product Name Alternative

Ritonavir, SARS coronavirus, SARS-CoV 3CLPpro, SARS-CoV, Veruprevir, 1221573-85-8, ABT450, ABT-450, ABT 450, CYP450, Inhibitor, HCV 1a, HCV 1b, HCV genotype 1a, HCV genotype 1b, HCV, HCVProtease, HCV Protease, HCV NS3/4A, Hepatitis C virus, inhibit, NS3/4A, Paritaprevir, orally active

Field of Research

Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry

Purity

98.04% (May vary between batches)

Solubility

DMSO:80 mg/mL (104.46 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (4.31 mM)

Smiles

Cc1cnc (cn1) C (=O) N[C@H]1CCCCC\C=C/[C@@H]2C[C@]2 (NC (=O) [C@@H]2C[C@H] (CN2C1=O) Oc1nc2ccccc2c2ccccc12) C (=O) NS (=O) (=O) C1CC1

Molecular Formula

C40H43N7O7S

Molecular Weight

765.88

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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