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1- (4-Chloro-3- (trifluoromethyl) phenyl) -3- (4- (4-cyanophenoxy) phenyl) urea

SC-1 is a sorafenib-derived small molecule that potently inhibits STAT3 phosphorylation and activation, leading to apoptosis in hepatocellular carcinoma cells. It is used in cancer research, particularly for studying STAT3 signaling pathways in vitro.

Product Specifications

CAS Number

1313019-65-6

Product Name Alternative

Cyclin-D1, Apoptosis, anticancer, 1 (4 Chloro 3 (trifluoromethyl) phenyl) 3 (4 (4 cyanophenoxy) phenyl) urea, 1 (4Chloro3 (trifluoromethyl) phenyl) 3 (4 (4cyanophenoxy) phenyl) urea, kinase, Inhibitor, inhibit, orally, SHP-1, p-STAT3, survivin, STAT, STAT3

Field of Research

Cell Biology, Kidney & Urological Research, Signal Transduction, Stem Cell & Developmental Biology

Purity

97.56% (May vary between batches)

Solubility

DMSO:55 mg/mL (127.37 mM)

Smiles

FC (F) (F) C1=CC (NC (=O) NC2=CC=C (OC3=CC=C (C=C3) C#N) C=C2) =CC=C1Cl

Molecular Formula

C21H13ClF3N3O2

Molecular Weight

431.8

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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