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SU5204

SU5204 is a small molecule VEGFR2 (FLK-1) inhibitor with an IC50 of 4 μM, and it also inhibits HER2 (IC50 = 51.5 μM) . This SU5025 analogue is a useful research tool for studying angiogenesis and oncology in both cellular and animal models.

Product Specifications

CAS Number

186611-11-0

Product Name Alternative

3-[ (2-Ethoxyphenyl) methylidene]-1H-indol-2-one, inhibit, EGFR, ErbB-1, Epidermal growth factor receptor, Inhibitor, HER1, HER2, SU 5204, SU5204, SU-5204, VEGFR, VEGFR2, Vascular endothelial growth factor receptor

Field of Research

Cardiovascular Research, Signal Transduction

Purity

99.46% (May vary between batches)

Solubility

DMSO:27.5 mg/mL (103.65 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.54 mM)

Smiles

CCOc1ccccc1C=C1C (=O) Nc2ccccc12

Molecular Formula

C17H15NO2

Molecular Weight

265.31

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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