Tyrphostin B44, (+) enantiomer
The (+) enantiomer of Tyrphostin B44 is a selective EGFR kinase inhibitor exhibiting an IC50 of 0.86 μM. It demonstrates lower potency compared to its (-) enantiomer counterpart. This compound is a valuable research tool for studying EGFR signaling in cancer biology through in vitro enzymatic and cellular assays.
Product Specifications
CAS Number
133550-37-5
Product Name Alternative
Tyrphostin AG 835, Tyrphostin B 50, Tyrphostin B44, enantiomer, Tyrphostin B44, (+) enantiomer, Tyrphostin B-44, (+) enantiomer, Tyrphostin B50, Tyrphostin B-50, Tyrphostin AG835, Tyrphostin AG-835, inhibit, non-metastatic tumors, INBL, Inhibitor, HER1, ErbB-1, EGFR, Epidermal growth factor receptor, antitumor, CALO, (+) -Tyrphostin B44, cervical carcinoma cell
Field of Research
Cardiovascular Research, Signal Transduction
Purity
97.18% (May vary between batches)
Solubility
DMSO:60 mg/mL (194.6 mM) ;10% DMSO+90% Saline:2.5 mg/mL (8.11 mM)
Smiles
C[C@H] (NC (=O) C (=C\c1ccc (O) c (O) c1) \C#N) c1ccccc1
Molecular Formula
C18H16N2O3
Molecular Weight
308.33
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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