XEN445
XEN445 is a potent and selective endothelial lipase inhibitor with an IC50 of 0.237 μM. It demonstrates favorable pharmacokinetic and ADME profiles, making it a useful chemical probe for researching lipid metabolism and cardiovascular diseases in both in vitro and in vivo models.
Product Specifications
CAS Number
1515856-92-4
Product Name Alternative
Inhibitor, inhibit, endothelial lipase, XEN 445, XEN445, XEN-445
Field of Research
Metabolism Research
Purity
99.47% (May vary between batches)
Solubility
Ethanol:36.6 mg/mL (99.91 mM) ; DMSO:60 mg/mL (163.79 mM)
Smiles
OC (=O) c1cc (ccc1N1CC[C@@H] (C1) OCc1ccccn1) C (F) (F) F
Molecular Formula
C18H17F3N2O3
Molecular Weight
366.33
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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