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NVP-TAE 684

NVP-TAE 684 (TAE684) is a potent and selective inhibitor of ALK with an IC50 of 3 nM. It is widely used in biochemical and cellular research to study ALK-driven signaling pathways and has demonstrated efficacy in preclinical models of ALK-positive cancers.

Product Specifications

CAS Number

761439-42-3

Product Name Alternative

CD246, Cluster of differentiation 246, ALK, ALK tyrosine kinase receptor, Anaplastic lymphoma kinase, Anaplastic lymphoma kinase (ALK), Apoptosis, inhibit, NVP TAE 684, NVPTAE 684, NVP-TAE 684, NVP-TAE684, NVP-TAE-684, Inhibitor, TAE 684, TAE684, TAE-684

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Purity

98.00% (May vary between batches)

Solubility

DMSO:7.27 mg/mL (11.84 mM)

Smiles

N (C1=C (S (C (C) C) (=O) =O) C=CC=C1) C2=NC (NC3=C (OC) C=C (C=C3) N4CCC (CC4) N5CCN (C) CC5) =NC=C2Cl

Molecular Formula

C30H40ClN7O3S

Molecular Weight

614.2

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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