NVP-TAE 684
NVP-TAE 684 (TAE684) is a potent and selective inhibitor of ALK with an IC50 of 3 nM. It is widely used in biochemical and cellular research to study ALK-driven signaling pathways and has demonstrated efficacy in preclinical models of ALK-positive cancers.
Product Specifications
CAS Number
761439-42-3
Product Name Alternative
CD246, Cluster of differentiation 246, ALK, ALK tyrosine kinase receptor, Anaplastic lymphoma kinase, Anaplastic lymphoma kinase (ALK), Apoptosis, inhibit, NVP TAE 684, NVPTAE 684, NVP-TAE 684, NVP-TAE684, NVP-TAE-684, Inhibitor, TAE 684, TAE684, TAE-684
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
DMSO:7.27 mg/mL (11.84 mM)
Smiles
N (C1=C (S (C (C) C) (=O) =O) C=CC=C1) C2=NC (NC3=C (OC) C=C (C=C3) N4CCC (CC4) N5CCN (C) CC5) =NC=C2Cl
Molecular Formula
C30H40ClN7O3S
Molecular Weight
614.2
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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