TCS PIM-1 1
TCS PIM-1 1 (SC 204330) is a potent and selective ATP-competitive inhibitor of Pim-1 kinase, with an IC50 of 50 nM. It demonstrates high specificity, showing minimal activity against Pim-2 and MEK1/2 (IC50 >20 μM) . This inhibitor is a valuable research tool for studying Pim-1's role in cancer and hematopoiesis in both cellular and animal models.
Product Specifications
CAS Number
491871-58-0
Product Name Alternative
ATP-competitive, Inhibitor, pyridone, inhibit, SC 204330, scaffold, SC204330, SC-204330, TCS PIM 1 1, TCS PIM1 1, TCS PIM-1 1, Pim kinases, Pim1, Pim-1, Pim
Field of Research
Cell Biology, Epigenetics & Chromatin, Signal Transduction
Purity
97.00% (May vary between batches)
Solubility
DMSO:16.67 mg/mL (45.4 mM)
Smiles
Oc1ccc (Br) cc1-c1cc (-c2ccccc2) c (C#N) c (=O) [nH]1
Molecular Formula
C18H11BrN2O2
Molecular Weight
367.2
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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