SB-743921 hydrochloride
SB-743921 hydrochloride is a potent and selective inhibitor of kinesin spindle protein (KSP) with a Ki of 0.1 nM. It induces mitotic arrest and has demonstrated antitumor activity in both cellular assays and in vivo xenograft models, making it a valuable tool for cancer research.
Product Specifications
CAS Number
940929-33-9
Product Name Alternative
SB743921 HCl, SB-743921 Hydrochloride, KSP, KSP (Colo205 cells), KSP (MV522 cells), KSP (MX1 cells), KSP (SKOV3 cells), Kinesin
Field of Research
Cell Biology, Signal Transduction
Purity
≥95% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.61 mM) ; DMSO:60 mg/mL (108.4 mM)
Smiles
Cl.CC (C) [C@@H] (N (CCCN) C (=O) c1ccc (C) cc1) c1oc2cc (Cl) ccc2c (=O) c1Cc1ccccc1
Molecular Formula
C31H34Cl2N2O3
Molecular Weight
553.52
Storage Conditions
-20°C
Notes
For research use only.
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