Silmitasertib
Silmitasertib (CX-4945) is a highly potent and orally bioavailable small molecule inhibitor of casein kinase 2 (CK2), demonstrating a Ki of 0.38 nM. It is widely used in cancer research, showing antitumor activity in both cellular assays and in vivo models across various cancer types.
Product Specifications
CAS Number
1009820-21-6
Product Name Alternative
Silmitasertib, inhibit, Inhibitor, CK2, CX 4945, CX4945, CX-4945, Autophagy, Casein Kinase, CaseinKinase
Field of Research
Cell Biology, Metabolism Research, Stem Cell & Developmental Biology
Purity
≥95% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:17 mg/mL (48.6 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)
Smiles
OC (=O) c1ccc2c (c1) nc (Nc1cccc (Cl) c1) c1ccncc21
Molecular Formula
C19H12ClN3O2
Molecular Weight
349.77
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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