IM-12
IM-12 is a potent and selective small molecule inhibitor of GSK-3β with an IC50 of 53 nM. It acts as a canonical Wnt/β-catenin pathway activator and is a valuable chemical tool for studying Wnt signalling in stem cell biology, oncology, and neurological research, both in vitro and in vivo.
Product Specifications
CAS Number
1129669-05-1
Product Name Alternative
Inhibitor, Glycogen synthase kinase 3, Glycogen synthase kinase-3, GSK-3β, GSK3, GSK-3, inhibit, IM-12, IM 12, IM12
Field of Research
Stem Cell & Developmental Biology
Purity
>98%
Bioactivity
GSK-3β inhibitor
Form
Powder
Solubility
Soluble in DMSO (50 mg/ml)
Smiles
CN1C (=O) C (NCCc2ccc (F) cc2) =C (C1=O) c1c (C) [nH]c2ccccc12
Molecular Formula
C22H20FN3O2
Molecular Weight
377.4
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
3- (4-Fluorophenylethylamino) -1-methyl-4- (2-methyl-1H-indol-3-yl) -1H-pyrrole-2,5-dione
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