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Bimiralisib

Bimiralisib (PI3K-IN-2) is an orally active pan-PI3K and mTOR inhibitor with antineoplastic potential. It induces apoptosis and inhibits proliferation in PI3K/mTOR-hyperactive cancer cells, as demonstrated in various in vitro and in vivo oncology research models targeting this critical survival pathway.

Product Specifications

CAS Number

1225037-39-7

Product Name Alternative

Bimiralisib, 5- (4,6-dimorpholino-1,3,5-triazin-2-yl) -4- (trifluoromethyl) pyridin-2-amine, Mammalian target of Rapamycin, Inhibitor, mTOR, inhibit, S6 Kinase, S6Kinase, Phosphoinositide 3-kinase, pPKB, PQR309, PQR-309, PQR 309, pS6, PI3K, PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ, PI3K-IN-2

Field of Research

Signal Transduction

Purity

97.58% (May vary between batches)

Solubility

DMSO:5 mg/mL (12.15 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.43 mM)

Smiles

Nc1cc (c (cn1) -c1nc (nc (n1) N1CCOCC1) N1CCOCC1) C (F) (F) F

Molecular Formula

C17H20F3N7O2

Molecular Weight

411.38

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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