CHM-1
CHM-1 is a potent small molecule anticancer agent that induces apoptosis and exhibits antitumor activity in human hepatocellular carcinoma by activating Cdc2 kinase. It functions as a tubulin polymerization inhibitor, as demonstrated in both in vitro and in vivo studies, making it a valuable tool for cancer research, particularly in studying cell cycle disruption and cytoskeleton dynamics.
Product Specifications
CAS Number
154554-41-3
Product Name Alternative
Cdc2, CHM 1, CHM1, CHM-1, carcinoma, Apoptosis, antimitotic, antitumor, Microtubule Associated, Microtubule/Tubulin, microtubule-destabilizing, MicrotubuleAssociated, NSC 656158, NSC656158, NSC-656158, inhibit, Inhibitor, hepatocellular, Tubulin polymerization
Field of Research
Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.83% (May vary between batches)
Solubility
H2O:< 7.08 mg/mL; DMSO:1.42 mg/mL (5.01 mM)
Smiles
O=C1C2=C (NC (=C1) C3=C (F) C=CC=C3) C=C4C (=C2) OCO4
Molecular Formula
C16H10FNO3
Molecular Weight
283.25
Storage Conditions
-20°C
Notes
For research use only.
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