Muzolimine

Muzolimine (BAY-g 282) is a slow and long lasting diuresis agent. Muzolimine produces a diuresis in the loop of Henle and also shows anti-hypertensive and natriuresis effects. Muzolimine can be used for the research of cardiovascular disease[1][2].

Product Specifications

CAS Number

[55294-15-0]

Product Name Alternative

BAY-g 2821; Edrul

UNSPSC

12352005

Target

Sodium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/muzolimine.html

Purity

98.22

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(C1=CC(Cl)=C(Cl)C=C1)N2C(CC(N)=N2)=O

Molecular Formula

C11H11Cl2N3O

Molecular Weight

272.13

References & Citations

[1]Lorke D, Mürmann P. Pre-clinical toxicological studies with muzolimine. Curr Med Res Opin. 1976-1977;4 (10) :716-24.|[2]Geck P, Pfeiffer B. Inhibition of ion transport in Ehrlich cells by muzolimine. Naunyn Schmiedebergs Arch Pharmacol. 1986 Jul;333 (3) :323-9.