JNJ-42165279
JNJ-42165279 is a highly selective covalent inhibitor of the FAAH enzyme, demonstrating no significant activity (>50% inhibition at 10 μM) against a broad panel of 50 off-targets, including key CYPs and the hERG channel. This selectivity profile supports its utility as a precise pharmacological tool for in vitro and in vivo research investigating the endocannabinoid system, pain, and mood disorders.
Product Specifications
CAS Number
1346528-50-4
Product Name Alternative
RFAAH, inhibit, JNJ 42165279, JNJ42165279, JNJ-42165279, Inhibitor, hFAAH, Fatty acid amide hydrolase, FAAH, Autophagy
Field of Research
Cell Biology, Metabolism Research, Neuroscience
Purity
99.67% (May vary between batches)
Solubility
DMSO:45 mg/mL (109.54 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.5 mg/mL (6.09 mM)
Smiles
FC1 (F) Oc2ccc (CN3CCN (CC3) C (=O) Nc3cnccc3Cl) cc2O1
Molecular Formula
C18H17ClF2N4O3
Molecular Weight
410.8
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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