PF-CBP1 hydrochloride
PF-CBP1 hydrochloride is a potent and selective bromodomain inhibitor of CREBBP and its paralog p300, with IC50 values of 125 nM and 363 nM, respectively. This small molecule is a valuable chemical probe for epigenetic research, used in vitro and in vivo to study the roles of these acetyl-lysine reader proteins in transcription, cell signaling, and disease models.
Product Specifications
CAS Number
2070014-93-4
Product Name Alternative
CREBBP, cortical, HistoneAcetyltransferase, Histone Acetyltransferase, HATs, HAT, Inhibitor, epilepsy, EpigeneticReaderDomain, Epigenetic Reader Domain, inhibit, inflammatory, p300/CBP, parkinson's disease, neuron, neurological disorder, RGS4, PF CBP1 hydrochloride, PF-CBP1, PF-CBP1 HCl, PFCBP1 hydrochloride, PF-CBP1 Hydrochloride, PF-CBP-1 hydrochloride
Field of Research
Cell Biology, Epigenetics & Chromatin
Purity
95.87% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.81 mM) ; DMSO:45 mg/mL (85.7 mM)
Smiles
Cl.CCCOc1ccc (CCc2nc3cc (ccc3n2CCN2CCOCC2) -c2c (C) noc2C) cc1
Molecular Formula
C29H37ClN4O3
Molecular Weight
525.08
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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