NLRP3i
NLRP3-IN-2 is a chemical intermediate for glibenclamide synthesis that specifically inhibits NLRP3 inflammasome assembly in cardiomyocytes. It has been shown to reduce myocardial infarct size in mouse models of ischemia/reperfusion injury without affecting metabolic parameters, making it a useful research tool for studying cardiovascular inflammation.
Product Specifications
CAS Number
16673-34-0
Product Name Alternative
JC121
Field of Research
Immunology & Inflammation, Neuroscience
Purity
>98%
Bioactivity
NLRP3 inflammasome inhibitor
Form
Powder
Solubility
Soluble in DMSO up to 45 mg/ml
Smiles
COc1ccc (Cl) cc1C (=O) NCCc1ccc (cc1) S (N) (=O) =O
Molecular Formula
C16H17ClN2O4S
Molecular Weight
368.8
Storage Conditions
RT
Notes
For research use only.
Other Product Names
4-[2- (5-Chloro-2-methoxybenzamido) ethyl]phenylsulfonamide
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