NVP-TNKS656
NVP-TNKS656 is a potent, selective, and orally bioavailable inhibitor of tankyrase 2 (TNKS2) . It is a valuable research tool for studying Wnt/β-catenin signaling in cancer biology and has demonstrated utility in both cellular assays and in vivo xenograft models.
Product Specifications
CAS Number
1419949-20-4
Product Name Alternative
Wnt/β-catenin, Wnt/b-catenin, Wnt/betacatenin, Wnt, poly ADP ribose polymerase, TNKS 656, TNKS656, TNKS-656, TNKS2, βcatenin, beta-catenin, betacatenin, bcatenin, Apoptosis, Inhibitor, PARP, NVP TNKS656, NVP-TNKS 656, NVPTNKS656, NVP-TNKS656, NVP-TNKS-656, inhibit
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
96.79% (May vary between batches)
Solubility
DMSO:93 mg/mL (188.04 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.67 mM) ; Ethanol:10 mg/mL (20.22 mM)
Smiles
COc1ccc (cc1) C (=O) C1CCN (CC (=O) N (CC2CC2) Cc2nc3CCOCc3c (=O) [nH]2) CC1
Molecular Formula
C27H34N4O5
Molecular Weight
494.58
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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