S49076
S49076 is a novel small molecule inhibitor targeting receptor tyrosine kinases MET, AXL/MER, and FGFR1/2/3. It effectively blocks their cellular phosphorylation and has demonstrated activity in preclinical in vitro and in vivo cancer models, supporting its use in oncology research.
Product Specifications
CAS Number
1265965-22-7
Product Name Alternative
Inhibit, Mer, Met, Fibroblast growth factor receptor, FGFR, FGFR3, FGFR2, Inhibitor, HGFR, c-Met/HGFR, c-Met, cMet/HGFR, cMet, AXL, S49076, S-49076, S 49076, TAMReceptor, TAM Receptor
Field of Research
Cardiovascular Research, Signal Transduction
Purity
91.88% (May vary between batches)
Solubility
DMSO:81 mg/mL (184.72 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.53 mM)
Smiles
O=C1CSC (=O) N1Cc1ccc2NC (=O) \C (=C/c3cc (CN4CCOCC4) c[nH]3) c2c1
Molecular Formula
C22H22N4O4S
Molecular Weight
438.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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