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Dizocilpine Maleate

Dizocilpine Maleate (MK-801 maleate) is a potent, selective, non-competitive NMDA receptor antagonist with a Kd of 37.2 nM. It is widely used in neuroscience research to study excitotoxicity, neurodegenerative mechanisms, and to establish pharmacological models of schizophrenia in both in vitro and in vivo experimental systems.

Product Specifications

CAS Number

77086-22-7

Product Name Alternative

Noncompetitive, inhibit, Ionotropic glutamate receptors, MK 801, MK 801 Maleate, neurotransmitter, MK-801, MK801, Mk-801 Hydrogen Maleate, MK801 Maleate, MK-801 Maleate, NMDA receptor, iGluR, hyperlocomotion, Inhibitor, Dizocilpine, Dizocilpine hydrogen maleate, Dizocilpine hydrogen Maleate, Dizocilpine Maleate, (+) -MK 801 (Maleate), (+) -MK 801 maleate, (+) -Mk-801 Hydrogen Maleate, ambulation, anticonvulsant, voltage

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

99.00% (May vary between batches)

Solubility

DMSO:250 mg/mL (741 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.93 mM)

Smiles

OC (=O) \C=C/C (O) =O.C[C@]12N[C@H] (Cc3ccccc13) c1ccccc21

Molecular Formula

C20H19NO4

Molecular Weight

337.38

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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