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Velpatasvir

Velpatasvir (GS-5816) is a pan-genotypic HCV NS5A inhibitor with a high barrier to resistance. It is widely used in antiviral research, demonstrating potent activity in both in vitro replicon assays and in clinical studies for genotypes 1-6, and is a key component of combination therapies.

Product Specifications

CAS Number

1377049-84-7

Product Name Alternative

GS-5816

Field of Research

Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry

Purity

>98%

Bioactivity

Hepatitis C protease inhibitor

Form

Powder

Solubility

Soluble in DMSO (up to 25 mg/ml)

Smiles

COC[C@H]1C[C@H] (N (C1) C (=O) [C@H] (NC (=O) OC) c1ccccc1) c1ncc ([nH]1) -c1ccc-2c (COc3cc4c5[nH]c (nc5ccc4cc-23) [C@@H]2CC[C@H] (C) N2C (=O) [C@@H] (NC (=O) OC) C (C) C) c1

Molecular Formula

C49H54N8O8

Molecular Weight

883.0

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

Methyl [ (2S) -1-[ (2S,5S) -2-[9-[2-[ (2S,4S) -1-[ (2R) -2-[ (methoxycarbonyl) amino]-2-phenylacetyl]-4- (methoxymethyl) pyrrolidin-2-yl]-1H-imidazol-5-yl]-1,11-dihydroisochromeno[4',3':6,7]naphtho[1,2-d]imidazol-2-yl]-5-methylpyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate

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