Rg3039
RG3039 (PF-06687859) is a potent and selective DcpS inhibitor developed for spinal muscular atrophy (SMA) research. It has demonstrated efficacy in preclinical studies, improving survival, motor function, and neuromuscular pathology in SMA mouse models, supporting its investigation as a potential therapeutic strategy.
Product Specifications
CAS Number
1005504-62-0
Product Name Alternative
Inhibitor, inhibit, DcpS, RG 3039, Rg3039, Rg-3039, PF06687859, PF-06687859, PF 06687859
Field of Research
Cell Biology, Molecular Biology
Purity
98.24% (May vary between batches)
Solubility
H2O:< 0.1 mg/mL (insoluble) ; DMSO:1 mg/mL (2.31 mM)
Smiles
Nc1nc (N) c2c (OCC3CCN (Cc4c (Cl) cccc4Cl) CC3) cccc2n1
Molecular Formula
C21H23Cl2N5O
Molecular Weight
432.35
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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