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Rg3039

RG3039 (PF-06687859) is a potent and selective DcpS inhibitor developed for spinal muscular atrophy (SMA) research. It has demonstrated efficacy in preclinical studies, improving survival, motor function, and neuromuscular pathology in SMA mouse models, supporting its investigation as a potential therapeutic strategy.

Product Specifications

CAS Number

1005504-62-0

Product Name Alternative

Inhibitor, inhibit, DcpS, RG 3039, Rg3039, Rg-3039, PF06687859, PF-06687859, PF 06687859

Field of Research

Cell Biology, Molecular Biology

Purity

98.24% (May vary between batches)

Solubility

H2O:< 0.1 mg/mL (insoluble) ; DMSO:1 mg/mL (2.31 mM)

Smiles

Nc1nc (N) c2c (OCC3CCN (Cc4c (Cl) cccc4Cl) CC3) cccc2n1

Molecular Formula

C21H23Cl2N5O

Molecular Weight

432.35

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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