Ddr1-In-1
DDR1-IN-1 is a potent and selective small molecule inhibitor of the DDR1 kinase, demonstrating an IC50 of 105 nM and approximately 3-fold selectivity against DDR2. This tool compound is useful for investigating the role of DDR1 in fibrotic diseases and cancer progression in both cellular and animal models.
Product Specifications
CAS Number
1449685-96-4
Product Name Alternative
Inhibitor, inhibit, Discoidin Domain Receptor, Discoidin Domain Receptor (DDR), DiscoidinDomainReceptor, DiscoidinDomainReceptor (DDR), Ddr1 In 1, DDR1, DDR, Ddr1In1, Ddr-1-In-1, Ddr1-In-1, DDR2
Field of Research
Signal Transduction
Purity
99.34% (May vary between batches)
Solubility
Ethanol:4 mg/mL (7.24 mM) ; DMSO:26.67 mg/mL (48.26 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (5.97 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
CCN1CCN (Cc2ccc (cc2C (F) (F) F) C (=O) Nc2ccc (C) c (Oc3ccc4NC (=O) Cc4c3) c2) CC1
Molecular Formula
C30H31F3N4O3
Molecular Weight
552.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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