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Ceralasertib

Ceralasertib (AZD6738) is a potent and selective orally active ATR kinase inhibitor with a reported IC50 of 1 nM. It demonstrates antitumor activity in preclinical research, being utilized in both in vitro and in vivo studies to investigate DNA damage response pathways and combination therapies in oncology.

Product Specifications

CAS Number

1352226-88-0

Product Name Alternative

Ceralasertib, Ataxia telangiectasia mutated, ATM, ATM/ATR, ATM and RAD3 related, AZD 6738, AZD-6738, AZD6738, ATR, inhibit, Inhibitor

Field of Research

Molecular Biology, Signal Transduction

Purity

98.00% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:7.6 mg/mL (18.42 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:39 mg/mL (94.54 mM) ; DMSO:250 mg/mL (606.05 mM)

Smiles

C[C@@H]1COCCN1c1cc (nc (n1) -c1ccnc2[nH]ccc12) C1 (CC1) S (C) (=N) =O

Molecular Formula

C20H24N6O2S

Molecular Weight

412.51

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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