Ceralasertib
Ceralasertib (AZD6738) is a potent and selective orally active ATR kinase inhibitor with a reported IC50 of 1 nM. It demonstrates antitumor activity in preclinical research, being utilized in both in vitro and in vivo studies to investigate DNA damage response pathways and combination therapies in oncology.
Product Specifications
CAS Number
1352226-88-0
Product Name Alternative
Ceralasertib, Ataxia telangiectasia mutated, ATM, ATM/ATR, ATM and RAD3 related, AZD 6738, AZD-6738, AZD6738, ATR, inhibit, Inhibitor
Field of Research
Molecular Biology, Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:7.6 mg/mL (18.42 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:39 mg/mL (94.54 mM) ; DMSO:250 mg/mL (606.05 mM)
Smiles
C[C@@H]1COCCN1c1cc (nc (n1) -c1ccnc2[nH]ccc12) C1 (CC1) S (C) (=N) =O
Molecular Formula
C20H24N6O2S
Molecular Weight
412.51
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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