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PIK-293

PIK-293 is a selective small molecule inhibitor of phosphoinositide 3-kinase delta (PI3Kδ) with an IC50 of 0.24 μM, demonstrating lower activity against the PI3Kα, β, and γ isoforms. This compound is a valuable research tool for studying PI3Kδ signaling in immunological and oncological contexts, applicable in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

900185-01-5

Product Name Alternative

PIK293, PIK-293, PIK 293, PI3K, Phosphoinositide 3-kinase, Inhibitor, inhibit, p110δ, p110γ, p110β, p110α

Field of Research

Signal Transduction

Purity

99.65% (May vary between batches)

Solubility

DMSO:80 mg/mL (201.29 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.03 mM)

Smiles

Cc1ccccc1-n1c (Cn2ncc3c (N) ncnc23) nc2cccc (C) c2c1=O

Molecular Formula

C22H19N7O

Molecular Weight

397.43

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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