MTOB
MTOB (α-keto-γ-Methylthiobutyric acid) is a small molecule inhibitor of the transcriptional co-repressor CtBP, disrupting its oncogenic functions. It has been shown to inhibit cancer cell proliferation and modulate TCF-4/Wnt signaling pathways in both cellular assays and in vivo mouse models, making it a valuable research tool for studying cancer stemness and tumorigenesis.
Product Specifications
CAS Number
51828-97-8
Product Name Alternative
CtBP, 4-methylthio 2-oxobutyric acid, 4-methylthio 2-oxobutyric acid sodium salt, a-keto-r-Methylthiobutyric acid, alpha-keto-gamma-Methylthiobutyric acid, KMBA, MTOB, MTOB salt, MTOB sodium salt, TBI, traumatic brain injury, α-keto-γ-Methylthiobutyric acid, α-keto-γ-Methylthiobutyric acid sodium salt
Field of Research
Cell Biology, Molecular Biology
Purity
98.23% (May vary between batches)
Solubility
DMSO:55 mg/mL (323.23 mM) ; PBS:100 mg/mL (587.68 mM)
Smiles
[Na+].CSCCC (=O) C ([O-]) =O
Molecular Formula
C5H7NaO3S
Molecular Weight
170.16
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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