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MTOB

MTOB (α-keto-γ-Methylthiobutyric acid) is a small molecule inhibitor of the transcriptional co-repressor CtBP, disrupting its oncogenic functions. It has been shown to inhibit cancer cell proliferation and modulate TCF-4/Wnt signaling pathways in both cellular assays and in vivo mouse models, making it a valuable research tool for studying cancer stemness and tumorigenesis.

Product Specifications

CAS Number

51828-97-8

Product Name Alternative

CtBP, 4-methylthio 2-oxobutyric acid, 4-methylthio 2-oxobutyric acid sodium salt, a-keto-r-Methylthiobutyric acid, alpha-keto-gamma-Methylthiobutyric acid, KMBA, MTOB, MTOB salt, MTOB sodium salt, TBI, traumatic brain injury, α-keto-γ-Methylthiobutyric acid, α-keto-γ-Methylthiobutyric acid sodium salt

Field of Research

Cell Biology, Molecular Biology

Purity

98.23% (May vary between batches)

Solubility

DMSO:55 mg/mL (323.23 mM) ; PBS:100 mg/mL (587.68 mM)

Smiles

[Na+].CSCCC (=O) C ([O-]) =O

Molecular Formula

C5H7NaO3S

Molecular Weight

170.16

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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